Process Safety Assessment and Control
- Hazard and risk assessment integrated into all projects.
- SOPs governing processes for risk assessment, planning and scale-up operations.
- Process safety evaluation in a dedicated process safety lab.
- Thermoanalytical: DSC (inputs, outputs and reaction mixtures).
- Calorimetry: ARSST and RC1e (reaction mixtures; Mettler-Toledo).
Application for Scale-up
Scale-up in the kilo lab/pilot plant requires:
- Process description (experimental procedure).
- HAZOP assessment (Hazard and Operability Study).
- Process flow chart.
- Batch production record.
- Safety training.
- Process Chemical Safety Review (PCSR) prior to scale-up with a Chemical Hazard Assessment Report (CHAR) generated.
- Project Manufacturing Procedure (PMP) and related documentation for plant operations.